Endocrine Abstracts

We are all aware of the current anxieties over the future of Academic Medicine and Modernising Medical Careers. 10 years ago the BMA cohort of 1995 Medical graduates: Medical Academic Career Intentions was performed. 545 doctors graduating in 1995 were followed up for 10 years. The key findings included: those doctors working in research were doing so to improve future career prospects or as a means to secure a National Training Number (NTN). However being in the transition pe...

: Ectopic parathyroid adenomas have a low imaging incidence quoted at 1.4% in patients undergoing investigation for primary hyperparathyroidism with a prevalence of 6–30%. These are reported to have a more clinically severe manifestation of the disease, frequently with higher calcium levels and bone disease. Remission due to parathyroid infarction is a rare occurrence. We report a 54-yr Afro-Carribean/mixed race female who presented with lethargy, weight loss and reduced ...

: Ectopic parathyroid adenomas have a low imaging incidence quoted at 1.4% in patients undergoing investigation for primary hyperparathyroidism with a prevalence of 6–30%. These are reported to have a more clinically severe manifestation of the disease, frequently with higher calcium levels and bone disease. Remission due to parathyroid infarction is a rare occurrence. We report a 54-yr Afro-Carribean/mixed race female who presented with lethargy, weight loss and reduced ...

Armour thyroid is desiccated porcine extract which is a historical treatment for hypothyroidism. It contains both L-thyroxine and liothyronine. Each grain (60 mg) contains 38 μg of L-thyroxine and 9 μg liothyronine. Since the 1960’s its use has been superseded by L-thyroxine. Due to limited clinical effectiveness studies, it is not licensed for use in the United Kingdom. We present a case of Armour thyroid use in preg...

Introduction: Testogel is now established treatment for male hypogonadism. The aim of TRT is to resolve hypogonadal symptoms and achieve physiological levels of testosterone.Objective: To determine the efficacy of Testogel 50 mg/day, in achieving symptomatic benefit and physiological testosterone level in 100 male patients.Method: Retrospective review of 100 case notes from the andrology clinic. Men included were between 16 and 80 ...

Neuroendocrine tumours are rare, with an incidence of 8/100,000 in the UK. They result from excessive proliferation of neuroendocrine cells and are classified based on their site of origin, differentiation and clinical syndrome. Giant cell arteritis (GCA), a systemic vasculitis of unknown aetiology, rarely appears as a paraneoplastic syndrome. It is histologically characterised by granulomatous infiltrates with multinucleated giant cells at the intima media junction. The relat...

Introduction: The COVID-19 pandemic has affected the delivery of NET services and patient care. We retrospectively analysed the recovery of NET service provision over the COVID-19 recovery period 2020-2021.Method: The NET database was searched using 3 NET physician codes. Anonymised data was analysed, including PRRT, MIBG, endoscopy and bronchoscopy rates. In February 2022, patient satisfaction questionnaires were posted out to 87 randomly selected NET p...

Introduction: PNETs are rare with an annual incidence of 5 per million population. 75 % of pancreatic NET are functioning, PTHrP secretion regarded as a rarer entity and few case reports have been identified worldwide. Surgical resection is definitive management, however SSA treatment and Peptide Receptor Radionuclide Therapy (PRRT) have shown promising results in reducing PTHrP secretion.Case report: Here we describe a 61 years old lady who presented wi...

Insulin autoimmune syndrome (Hirata syndrome) is a rare cause of hypoglycaemia. It was described by Hirata in 1970 and characterised as spontaneous hypoglycaemia, with elevated insulin levels, and associated high titres of insulin autoantibodies. It is most commonly reported in Japan and is associated with autoimmune disease or exposure to sulfhydryl-containing drugs.Continuous glucose monitoring (CGM) devices measure interstitial glucose and were initia...

Pulmonary neuroendocrine tumors (NET) are well recognized, but quite an uncommon group of disorders to cause ectopic Cushing’s syndrome. Pulmonary NETs have also undergone a change in treatment paradigms. We present a 62 year old female with incidentally detected left lower lobe lung nodule with biopsy proven well differentiated NET with ki67 index of 5–10% in 2011. She had a metachronous slow growing left sided renal tumor (hypernephroma), long standing type 2 diabe...